AKT1, PIK3CA, PTEN - somatic profiling
What's included in the price
- NGS sequencing — analysis of the full coding sequence
- In-house result interpretation by our own team
- Collection at our Point or free courier return of material
- Result available online in the patient portal (PDF)
A consultation with a clinical geneticist is available as a separate service. See the clinic
About this test
Accumulation of DNA mutations occurs prior to the transformation from a normal cell into a cancerous cell. These genetic changes can determine the management of the disease.
In this test, using genome sequencing, whole coding sequences of the AKT1, PIK3CA and PTEN genes are analyzed. Both somatic and germinal variants can be found in this test, but it doesn’t differentiate one from another. The result may be especially valuable for determining the most suitable management of breast cancer.
To perform the test we need paraffine block with the cancer tissue and pathology slides made of this block or blood for cfDNA.
Genes analysed (3)
| Gene | Inheritance | Associated condition |
|---|---|---|
| AKT1 | autosomal dominant | Cowden syndrome 6, Proteus syndrome, somatic |
| PIK3CA | autosomal dominant | Cowden syndrome 6 |
| PTEN | autosomal dominant | Cowden syndrome 6 |
Click a gene to see a single-gene test.
How the test works
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1
Order online
No referral needed. You order online.
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2
Collect the sample
Sample: Blood for cfDNA or Tissue block (FFPE) with preparations. Blood — at our Collection Point; block/slide — you deliver it (free courier return).
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3
Result
Available in 31 working days from sample registration in laboratory, online.
Frequently asked questions
How long does the AKT1, PIK3CA, PTEN - somatic profiling test take?
The result is usually available within 31 working days from sample registration in laboratory.
Do I need a referral?
No. You can order this genetic test online without a referral.
How many genes does this panel cover?
The panel analyses 3 genes.
How much does the test cost?
The price of the test is 1994 PLN.
Ready to order AKT1, PIK3CA, PTEN - somatic profiling
Order online — no referral needed.